Skip to main content
. 2022 May 8;14(5):1000. doi: 10.3390/v14051000

Figure 5.

Figure 5

Injury enhanced, but was not necessary, for MmuPV1-induced laryngeal disease in NSG mice. Infected groups week 1 and later only, n = 7–10 mice per group per timepoint. (A) Laryngeal disease incidence after laryngeal MmuPV1 infection vs. vocal fold abrasion and infection. * Significant Fisher’s exact test of group difference in dysplasia incidence in the larynx: week 4, p = 0.0198. All other p > 0.05. (B) Laryngeal disease severity after laryngeal MmuPV1 infection vs. vocal fold abrasion and infection. Severity was coded ordinally: negative = 0, mild dysplasia = 1, moderate dysplasia = 2, severe dysplasia = 3, invasive cancer = 4. * One-tailed Wilcoxon rank-sum tests of severity in Abrasion + MmuPV1 vs. MmuPV1 at each timepoint: week 4, p = 0.0083; week 8, p = 0.0313. All other p > 0.05.