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. 2022 May 14;11(10):2774. doi: 10.3390/jcm11102774

Table 2.

Differences in lifestyle and health status among transgender individual with and without self-reported STIs.

All
(n = 705)
% (n)
At Least One STI
(n = 48)
% (n)
No STI
(n = 657)
% (n)
p HR [95% Confidence Interval] Adjusted p
Smoking status
Ex-smoker 15.7% (111) 13.0% (6) 15.9% (104) p = 0.610 0.664 [0.267–1.653] p = 0.379
Current smoker 45.5% (321) 54.3% (26) 44.9% (295) p = 0.215 1.435 [0.772–2.668] p = 0.253
Comorbilities
Cardiovascular disease 1.6% (11) 4.3% (2) 1.4% (9) p = 0.128 1.525 [0.297–7.829] p = 0.613
Diabetes 1.1% (8) 2.1% (1) 1.1% (7) p = 0.512 1.389 [0.149–12.970] p = 0.773
Dyslipidemia 1.4% (10) 2.1% (1) 1.2% (8) p = 0.598 0.861 [0.101–7.322] p = 0.891
Hypertension 2.1% (15) 4.3% (2) 2.0% (13) p = 0.301 0.944 [0.195–4.572] p = 0.943
Cerebrovascular disease 0.4% (3) 0.0% (0) 0.5% (3) p = 0.641 0.000 [0.000-] p = 0.999
Current medication use 2.7% (19) 4.3% (2) 2.6% (17) p = 0.501 2.808 [0.597–13.212] p = 0.191
Alcohol consumption * 1.8% (13) 2.2% (1) 1.9% (12) p = 0.885 1.01 [0.122–8.343] p = 0.993
Lifetime substance abuse 31.4% (221) 50.0% (24) 30.0% (197) p = 0.003 2.552 [1.374–4.740] p = 0.003
Alcohol 11.9% (84) 8.3% (4) 12.2% (80) p = 0.492 0.788 [0.231–2.692] p = 0.704
Cannabis 19.4% (137) 22.9% (11) 19.2% (126) p = 0.668 1.504 [0.651–3.477] p = 0.339
Opiates 3.1% (22) 18.7% (9) 2.0% (13) p < 0.0001 8.673 [3.115–24.147] p < 0.0001
Cocaine 8.8% (62) 27.1% (13) 7.5% (49) p < 0.0001 4.608 [2.046–10.378] p < 0.0001
Hallucinogens 2.1% (15) 2.1% (1) 2.1% (14) p = 0.794 1.191 [0.148–9.573] p = 0.870
Ketamine 1.1% (8) 0.0% (0) 1.2% (8) p = 0.517 0.000 [0.000-] p = 0.999
Psychiatric disorders in the family 27.7% (195) 25.5% (12) 27.8% (183) p = 0.730 0.946 [0.470–1.903] p = 0.876
Sexual abuse
Childhood 6.8% (48) 6.4% (3) 6.9% (45) p = 0.886 0.757 [0.220–2.603] p = 0.659
Adolescence 4.7% (33) 14.9% (7) 4.0% (26) p = 0.001 4.178 [1.642–10.626] p = 0.003
Self-harming behaviors 28.0% (197) 29.2% (14) 27.8% (183) p = 0.705 1.350 [0.687–2.652] p = 0.384
Bullying
Childhood 15.0% (106) 8.3% (4) 15.5% (102) p = 0.215 0.693 [0.237–2.026] p = 0.503
Adolescence 17.3% (122) 6.5% (3) 18.1% (119) p = 0.046 0.519 [0.154–1.749] p = 0.290
Suicidal ideation 51.9% (366) 58.3% (28) 51.4% (338) p = 0.283 1.529 [0.819–2.857] p = 0.183
Current psychiatric medications 11.3% (80) 25.0% (12) 10.3% (68) p = 0.002 2.579 [1.237–5.380] p = 0.012
Antidepressants 6.5% (46) 8.3% (4) 6.4% (42) p = 0.555 1.108 [0.367–3.345] p = 0.856
Antipsychotics 1.4% (10) 2.1% (1) 1.4% (9) p = 0.680 1.249 [0.143–10.936] p = 0.841
Mood stabilizers 2.6% (18) 4.2% (2) 2.4% (16) p = 0.457 1.728 [0.349–8.556] p = 0.503
Benzodiazepines 4.5% (32) 12.5% (6) 4.0% (26) p = 0.006 3.072 [1.157–8.155] p = 0.024
Lifetime psychiatric disorders 21.5% (152) 37.5% (18) 20.4% (134) p = 0.010 1.988 [1.013–3.901] p = 0.046
GAD 2.0% (14) 0.0% (0) 2.1% (14) p = 0.339 0.000 [0.000-] p = 0.999
Depression 16.0% (113) 33.3% (16) 14.8% (97) p = 0.002 2.329 [1.154–4.701] p = 0.018
Dysthymia 0.1% (1) 0.0% (0) 0.2% (1) p = 0.790 0.000 [0.000-] p = 1.000
Bipolar disorder 1.1% (8) 0.0% (0) 1.2% (8) p = 0.479 0.000 [0.000-] p = 0.999
Panic disorder 4.3% (30) 2.1% (1) 4.4% (29) p = 0.510 0.368 [0.047–2.882] p = 0.341
Sociophobia 0.4% (3) 0.0% (0) 0.5% (3) p = 0.644 0.000 [0.000-] p = 0.999
PTSD 0.3% (2) 0.0% (0) 0.3% (2) p = 0.706 0.000 [0.000-] p = 0.999
OCD 0.9% (6) 0.0% (0) 0.9% (6) p = 0.513 0.000 [0.000-] p = 0.999
Any personality disorder 0.6% (4) 4.2% (2) 0.3% (2) p < 0.0001 13.176 [1.582–109.719] p = 0.017
Anorexia nervosa 0.9% (6) 2.1% (1) 0.8% (5) p = 0.319 4.585 [0.467–45.068] p = 0.192

Data are expressed as percentages, while the absolute number of subjects is reported in parentheses. Data have been adjusted for age. Logistic regression analysis after adjustment for age was performed. * More than 2 alcohol units per day. STI = sexually transmitted infection; GAD = generalized anxiety disorder; PTSD = post-traumatic stress disorder; OCD = obsessive-compulsive disorder.