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. 2022 May 18;23(10):5675. doi: 10.3390/ijms23105675

Figure 2.

Figure 2

Empagliflozin does not change visceral fat volume. Male and Female TallyHo (squares), SWR/J (triangles), and C57BL6J (circles) were fed a high milk-fat diet in the absence (filled symbols) or presence (open symbols) of 10 mg/kg BW Empagliflozin. MRI was performed to detect changes in visceral adiposity. Representative images of the abdominal region from male (A) and female (D) mice highlight the area quantified (dashed lines). (B,E) The total volume of the abdomen was quantified and graphed as thousands of voxels. (C,F) Within the abdominal region, the total volume of visceral fat was calculated. Two-way ANOVA with multiple comparisons was performed. * p < 0.05 TallyHo control mice vs. C57BL6J and SWR/J; † p < 0.05 TallyHo Empagliflozin vs. C57BL6J and SWR/J; ‡ p < 0.05 TallyHo Empagliflozin vs. C57BL6J.