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. 2022 Apr 21;14(5):911. doi: 10.3390/pharmaceutics14050911

Table 3.

Arrangement of the optimization of the ESON with the amount of ESO, surfactants blend, water, droplets size, and PdI values.

Formulation Droplets Size (nm) PdI Essential Oil (%) Surfactants (%) Water (%)
F1 397.60 ± 10.54 0.925 ± 0.05 2.5 7.5 90.0
F2 179.92 ± 9.31 0.560 ± 0.02 5.0 7.5 87.5
F3 286.43 ± 3.90 0.910 ± 0.03 7.5 5.0 87.5
F4 277.52 ± 4.53 0.527 ± 0.06 7.5 2.5 90.0
F5 246.10 ± 6.14 0.520 ± 0.05 5.0 2.5 92.5
F6 76.57 ± 4.32 0.438 ± 0.02 2.5 5.0 92.5
F7 144.93 ± 7.54 0.383 ± 0.03 5.0 10.0 85.0
F8 46.34 ± 5.63 0.481 ± 0.02 7.5 7.5 85.0
F9 27.15 ± 10.16 0.410 ± 0.03 7.5 10.0 82.5
F10 108.53 ± 8.21 0.412 ± 0.04 5.0 5.0 90.0

HBL: hydrophilic–lipophilic balance; PdI: Polydispersity index.