IS	Ischemic stroke
r-tPA	Recombinant tissue plasminogen activator
FDA	Food and drug administration
US	United States
BBB	Blood–brain barrier
TCM	Traditional chinese medicine
CIRI	Cerebral ischemia/reperfusion injury
ROS	Reactive oxygen species
JAK	Janus Kinase
STAT	Signal Transducer And Activator Of Transcription
IL-1β	Interleukin-1β
TNF-α	Tumor necrosis factor-α
IL-6	Interleukin-6
ICAM-1α	Intercellular cell adhesion molecule-1 α
EPO	Erythropoietin
ECF	Epidermal Growth Factor
PDGF	Platelet-derivedgrowthfactorreceptor
MCAO	Middle Cerebral Artery Occlusion
NF-κB	Nuclear Factor Kappa-B
TLR4	Toll Like Receptor 4
FOXO3a	Forkhead box O3
MPO	Myeloperoxidase
NLRP3	NOD-like receptor protein 3
HMGB1	High Mobility Group Box 1
MyD88	Myeloiddifferentiationfactor88
MAPK	Mitogen-Activated Protein Kinase
CytC	Cytochrome c
Bcl-2	B-cell lymphoma-2
Bax	Bcl2-associated x protein
JNK	Jun N-Terminal Kinase
ERK	Extracellular Signal-Regulated Kinase
CSL	CBF1/suppressor of hairless/Lag
NICD	Notch intracellular domain
HIF	Hypoxia-inducible factor
VEGF	Vascular endothelial growth factor
Nrf2	Nuclear Factor E2-Related Factor 2
NQO1	Nad(p)h quinone oxidoreductase
HO-1	Heme oxygenase-1
SOD	Superoxide dismutase
CAT	Catalase
GPX-Px	Glutathione peroxidase
GSH	Reduced glutathione
AMPK	Adenosine monophosphate
OGD/R	Oxygen-Glucose Deprivation/Re-Oxygenation
MDA	Malondialdehyde
PI3K	Phosphoinositide 3-kinase
Akt	Protein kinase B
mTOR	mammalian target of rapamycin
SIRT1	Silent mating type information regulation 2 homolog-1.
MMP9	Matrix Metalloproteinase 9