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. 2022 Apr 30;13(5):713. doi: 10.3390/mi13050713

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Relative concentration ratio (expressed as a percentage) of Nile red that remained in solution following continuous flow through unmodified PDMS microchannels or PDMS microchannels modified with Pluronic^® F127 (surface and bulk modifications), paraffin, thermal aging, and solvent extraction. Values show Mean ± SD from a minimum of two independent experiments (** p < 0.01; * p < 0.05 vs. paraffin modification). (b,c) Fluorescence intensity profiles obtained from the confocal micrographs following continuous flow of a 20 µM rhodamine B solution through (b) unmodified PDMS microchannels and (c) bulk-modified PDMS with sol–gel treatment using tetraethoxysilane (TEOS).