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. 2022 May 6;14(5):1003. doi: 10.3390/pharmaceutics14051003

Table 2.

Mean Particles Size, Polydispersity Index, Zeta Potential and entrapment efficiency of empty liposomes, luteolin loaded liposomes, empty chitosomes and Luteolin-loaded Chitosomes. Measurements are expressed as mean ± SD.

Formulation Code Particle Size (nm) ± SD PDI± SD Zeta Potential (mV) ± SD Entrapment Efficiency% ± SD
F1 (Empty Lip.) 184.6 ± 1.85 0.3014 ± 0.06 −24.9 ± 4.21 NA
F2 (Lip-LUT20 a) 212.3 ± 2.18 0.398 ± 0.09 −33.1 ± 2.11 80.6 ± 1.28
F3 (Lip-LUT40 b) 320.0 ± 4.23 0.407 ± 0.25 −31.6 ± 1.48 77.9 ± 1.33
F4 (LUT-CHS2% c) 347.2 ± 1.84 0.419 ± 0.04 28 ± 2.94 79.2 ± 2.54
F5 (LUT-CHS4% d) 412.8 ± 3.28 0.378 ± 0.07 37.4 ± 2.13 86.6 ± 2.05
F6 (LUT-CHS8% e) 473.1 ± 2.14 0.274 ± 0.03 36.2 ± 3.04 81.5 ± 1.77

a Luteolin load equivalent to 20 mg%, b Luteolin load equivalent to 40 mg%, c–e Luteolin-loaded chitosomes with different chitosomes concentrations (2, 4, 8 mg%. respectively) and luteolin loading of 20 mg%.