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. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: Am J Cardiol. 2021 May 24;151:51–56. doi: 10.1016/j.amjcard.2021.04.010

Table 1.

Demographic and Clinical Characteristics, Prevalence of Functional Bowel Disorders and Gastrointestinal Work-Up Characterisitcs in Patients with Brugada Syndrome/Drug-Induced Type 1 Brugada Electrocardiographic Pattern and Conrol Group

Variable Patients with BrS/DI-Type 1 BrP (n=148) Control Group (n=124) P-value
Demographic and Clinical Characteristics
 - Age (years) 42.8±11.4 40.6±12.2 0.135
 - Women 62 (41.9%) 64 (51.6%) 0.109
 - Presence of Arrhythmia 75 (50.7%) 66 (53.2%) 0.675
 - Presence of Co-Morbid Conditions 46 (31.1%) 17 (25.8%) 0.430
 - Presence of Migraine 96 (64.9%) 37 (29.8%) 8.64×10−9
Categories of Functional Bowel Disorders
 - Functional Bowel Disorders 64 (43.2%) 27 (21.8%) 1.86×10−4
  - Irritable Bowel Syndrome 37 (25%) 10 (8.1%) 2.34×10−4
   - Constipation subtype 17 (45.9%) 7 (70%) 0.177
   - Diarrhea subtype 11 (29.7%) 1 (10%) 0.204
   - Mix of Constipation and Diarrhea subtype 6 (16.2%) 1 (10%) 0.624
   - Undefined subtype 3 (8.1%) 1 (10%) 1.000
  - Functional Constipation 5 (3.4%) 2 (1.6%) 0.460
  - Functional Diarrhea 3 (2%) 2 (1.6%) 0.80
  - Functional Abdominal Bloating/Distension 19 (12.8%) 13 (10.5%) 0.548
  - Functional Constipation/Diarrhea/Abdominal Bloating/Distension 27 (18.2%) 17 (13.7%) 0.312
Gastrointestinal Work-Up in Patients with Functional Bowel Disorders *
 - History of Gastointestinal Consultations and Work-Up 38 (59.4%) 12 (44.4%) 0.191
 - History of Upper Endoscopy 24 (37.5%) 9 (33.3%) 0.706
 - History of Colonoscopy 11 (17.2%) 2 (7.4%) 0.223

Data are given as mean ± SD, number of patients and percentages.

* =

By Primary Care Physician and/or Gastroenterologist, BrS = Brugada syndrome, DI-Type 1 BrP = Drug-Induced Type 1 Brugada ECG pattern.