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. 2022 Jan 29;29(28):43114–43125. doi: 10.1007/s11356-021-18331-3

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© The Author(s) 2021

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Fig. 3 — Effect of acetamiprid and azoxystrobin on liver tissue of rats. A, B Histological sections of the liver of control rats showed normal liver central vein (CV) and a normal portal area (PA). Liver sections of the treated group with acetamiprid with different doses (C–E). C Low dose demonstrated hydropic degeneration (HD), D medium dose demonstrated infiltration of mononuclear cells (arrow), hypertrophied and edema of portal area (PA), E high dose demonstrated infiltration of mononuclear cells (arrow), hypertrophied and edema of portal area (PA). Liver sections of the treated group with azoxystrobin (F–H). F; low dose demonstrated hydropic degeneration (HD). G Medium dose demonstrated infiltration of mononuclear cells (arrow), hypertrophied, and edema of portal area (PA). H High dose demonstrated infiltration of mononuclear cells (arrow), hypertrophied, and edema of portal area (PA). (hematoxylin–eosin (H&E) stained, × 200)