. 2022 Jan 29;29(28):43114–43125. doi: 10.1007/s11356-021-18331-3

Table 2.

Rat’s serum oxidative/antioxidant biomarkers levels after 1 and 2 months of treatment by AC and AZ doses

Oxidative/antioxidant parameters		Acetamiprid doses			Azoxystrobin doses			Control
Levels (mg/mL)	Duration	1/10 LD50	1/20 LD50	1/40 LD50	1/10 LD50	1/20 LD50	1/40 LD50
Catalase	1^st month	35 ± 1.15 ^a	41.33 ± 1.45 ^a,b	46.67 ± 1.20 ^a,b	42.67 ± 1.45 ^a	42.67 ± 1.15 ^a,b	52.33 ± 0.20 ^a,b	55.5 ± 0.29
Catalase	2^nd month	31 ± 1.15 ^a	37.33 ± 0.88 ^a,b	42.67 ± 1.20 ^a,b	38.67 ± 1.45 ^a	45 ± 1.15 ^a,b	51.67 ± 0.88 ^a,b	59.5 ± 0.29
Superoxide dismutase	1^st month	46.67 ± 1.86^a	55.67 ± 1.76 ^a,b	65.33 ± 1.45 ^a,b	58 ± 1.53 ^a	68 ± 0.58 ^a,b	70.40 ± 0.31 ^a,b	74.67 ± 0.88
Superoxide dismutase	2^nd month	41.67 ± 1.86 ^a	49 ± 0.88 ^a,b	60.33 ± 1.45 ^a,b	53 ± 1.52 ^a	63 ± 0.8 ^a,b	68 ± 1.15 ^a	77.5 ± 0.29
Glutathione reductase	1^st month	28.67 ± 0.88 ^a	35.33 ± 1.45 ^a,b	40.8o ± 0.42 ^a,b	40 ± 0.58 ^a	43.50 ± 0.29 ^a,b	45.27 ± 0.37 ^a,b	48.5 ± 0.29
Glutathione reductase	2^nd month	23.67 ± 0.88 ^a	30.33 ± 1.45 ^a,b	36.33 ± 0.88 ^a,b	35.67 ± 1.20 ^a	40 ± 0.58 ^a,b	43 ± 0.67 ^a,b	55.5 ± 0.29
Nitric oxide	1^st month	72.33 ± 0.58 ^a	64.33 ± 0.88 ^a,b	57.67 ± 0.95 ^a,b	57 ± 0.88 ^a	45.67 ± 0.87 ^a,b	40.33 ± 0.88 ^a,b	33 ± 0.58
Nitric oxide	2^nd month	76.33 ± 0.88 ^a	68.33 ± 0.88 ^a,b	61.67 ± 0.88 ^a,b	61.67 ± 0.88 ^a	49.67 ± 0.88 ^a,b	44 ± 0.58 ^a,b	36.9 ± 0.08

Data presented as mean ± S.E (n = 4). ^a Significant difference of 1/10, 1/20, and 1/40 LD₅₀ as compared to the control group, ^b significant difference as compared to the 1/10 LD₅₀ group