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. 2022 May 28;12:8979. doi: 10.1038/s41598-022-12955-2

Table 2.

Clinical categorical variables related to SRL response.

Group SRL responsea Pearson χ2 p-valueb
CR PR NR
Presurgical hypopituitarism Yes 42% 15% 55% 0.01
No 68% 85% 45%
Presurgical visual alterations Yes 13% 27% 19% 0.62
No 87% 73% 81%
T2 signal intensity Hypointense 31% 22% 36% 0.90
Isointense 38% 56% 36%
Hyperintense 31% 22% 28%
T1 signal intensity Hypointense 61% 40% 53% 0.75
Isointense 39% 50% 38%
Hyperintense 0% 10% 8%
Gender Male 46% 35% 62% 0.07
Female 54% 65% 38%
GNAS mutation Mutated 29% 38% 36% 0.83
WT 71% 62% 64%
Sinus Invasion Yes 22% 35% 59% 0.05
No 78% 65% 41%
Extrasellar growth Yes 48% 60% 95% 0.004
No 52% 40% 5%

aSRL response columns indicate the percentage of patients with CR, PR, or NR dictated by the presence of absence of the clinical condition.

bPearson χ2 p-values are shown. Statistically significant values (p-value < 0.05) are reported in bold.