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. 2022 May 28;13(5):506. doi: 10.1038/s41419-022-04908-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A RBP-J expression in the microphages from glioma tissues and paired normal tissue samples (n = 40) using qRT-PCR. B Kaplan–Meier analysis of overall survival of glioma patients stratified by RBP-J expression. C Cell proliferation in glioma cell lines U87 MG co-cultured with WT Mφ, RBP-J OE Mφ, spaced RBP-J OE Mφ, spaced RBP-J OE Mφ-EVs or RBP-J OE Mφ-supernatant was assessed by CCK-8. D Wound healing assay is performed to detect cell migration (bar = 100 μm). All experiments were performed three times. **P < 0.01, ***P < 0.001 for statistical differences, EVs Extracellular vesicles, ns no significance.