Table 2.
Alpha diversity by the indices: Observed, Shannon and Inverse Simpson the between various cohorts.
| HIV cohort compared to the Pneumonia cohort | |||
|---|---|---|---|
| HIV (n = 20) | Pneumonia (n = 45) | p value* | |
| Observed | |||
| Median (IQR) | 279.5 (213.0–342.5) | 130.0 (74.0–240.0) | < 0.001** |
| Min / Max | 40.0/626.0 | 23.0/400.0 | |
| Shannon | |||
| Median (IQR) | 4.9 (4.4–5.0) | 3.8 (3.4–4.3) | < 0.001** |
| Min/max | 3.2/5.4 | 1.6/5.2 | |
| Inverse Simpson | |||
| Median (IQR) | 74.5 (47.4–94.6) | 18.4 (14.6–33.8) | < 0.001** |
| Min/max | 14.9/146.3 | 4.0 / 116.0 | |
| HIV cohort compared to the TB cohort | |||
|---|---|---|---|
| HIV (n = 20) | TB (n = 28) | p value* | |
| Observed | |||
| Median (IQR) | 279.5 (213.0–342.5) | 100.0 (65.0–147.0) | < 0.001** |
| Min/max | 40.0/626.0 | 24.0/299.0 | |
| Shannon | |||
| Median (IQR) | 4.9 (4.4–5.0) | 3.4 (3.0–3.9) | < 0.001** |
| Min/max | 3.2/5.4 | 2.3/4.9 | |
| Inverse Simpson | |||
| Median (IQR) | 74.5 (47.4–94.6) | 18.4 (14.6–33.8) | < 0.001** |
| Min/max | 14.9/146.3 | 6.0 / 65.1 | |
| Pneumonia cohort compared to the TB cohort | |||
|---|---|---|---|
| Pneumonia (n = 45) | TB (n = 28) | p value* | |
| Observed | |||
| Median (IQR) | 130.0 (74.0–240.0) | 100.0 (65.0–147.0) | 0.054 |
| Min/max | 23.0/400 | 24.0/299.0 | |
| Shannon | |||
| Median (IQR) | 3.8 (3.4–4.3) | 3.4 (3.0–3.9) | 0.054 |
| Min/max | 1.6/5.2 | 2.3/4.9 | |
| Inverse Simpson | |||
| Median (IQR) | 29.0 (16.0–40.1)–94.6) | 18.4 (14.6–33.8) | 0.101 |
| Min/max | 4.0/116.0 | 6.0/65.1 | |
*Nonparametric Wilcoxon rank sum test.
**Statistically significant.