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Crystal structures of de novo designed transmembrane oligomers. a) Model of the dimeric transmembrane protein, indicating the position of the amphipathic (YW) and positively charged (RK) rings. b) Comparison between the crystal structure and design model of a transmembrane dimer. c) Crystal structure and design model of the transmembrane tetramer. Adapted with permission from Ref.358. Copyright 2018 AAAS.
