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Genetic fusion approach to 2D protein assembly. Self-assembly of binary 2D arrays along the C2 symmetry axis shared by the components. The homologous D4-symmetric protein building block ALAD is combined with a) a heterologous D2-symmetric assembly motif (Streptavidin/Streptag I) or b) a heterologous C2-symmetric assembly motif (Lac21E/Lac21K). Adapted with permission from Ref.128. Copyright 2011 NPG.
