Computationally designed 2D lattices with p321, p4212, and p6 layer group symmetry (designs p3Z_42, p4Z_i9, p6_9H). a) Packing of the designed lattices with the representation of the unit cells. b) Schematic representations of the designed 2D arrays. c) Designed interfaces between protein building blocks. d) ns-TEM characterization of the designed 2D lattices. Inset: enlarged image and FFT of the ns-TEM image. e) Projection map calculated from (d), and the overlay of the designed model on the projection map. Adapted with permission from Ref.188. Copyright 2015 AAAS.