Table 5.

Functional enrichment analysis results. The 25 GO terms with the smallest Benjamini Hochberg (BH) adjusted p-values were selected for each cluster. The lists were then reduced to include only the most specific subclass for each ontology. All GO terms had a BH adjusted p-value < 0.01

GO Term	Description	# Genes in Set	# Genes in Cluster	# Expected	Fold Enrichment
Cluster 3
GO:0002523	leukocyte migration involved in inflammatory response	12	6	0.30	20.00
GO:0050729	positive regulation of inflammatory response	86	13	2.15	6.05
GO:0051092	positive regulation of NF-kappaB transcription factor activity	136	16	3.40	4.71
GO:1990266	neutrophil migration	79	12	1.98	6.06
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	33	7	0.83	8.43
GO:0045623	negative regulation of T-helper cell differentiation	14	5	0.35	14.29
GO:0060142	regulation of syncytium formation by plasma membrane fusion	14	5	0.35	14.29
GO:0071260	cellular response to mechanical stimulus	61	9	1.53	5.88
GO:0060396	growth hormone receptor signaling pathway	16	5	0.40	12.50
GO:0032651	regulation of interleukin-1 beta production	68	9	1.70	5.29
GO:0032695	negative regulation of interleukin-12 production	17	5	0.43	11.63
GO:0071354	cellular response to interleukin-6	28	6	0.70	8.57
Cluster 5
GO:0006958	complement activation, classical pathway	83	40	2.11	18.96
GO:0030449	regulation of complement activation	71	29	1.80	16.11
GO:0002377	immunoglobulin production	128	34	3.25	10.46
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	117	29	2.97	9.76
GO:0006910	phagocytosis, recognition	54	21	1.37	15.33
GO:0050871	positive regulation of B cell activation	111	25	2.82	8.87
Cluster 6
GO:0006910	phagocytosis, recognition	54	9	0.22	40.91
GO:0006958	complement activation, classical pathway	83	9	0.34	26.47
GO:0006911	phagocytosis, engulfment	87	9	0.35	25.71
GO:0016584	nucleosome positioning	11	4	0.04	100.00
GO:0030261	chromosome condensation	35	5	0.14	35.71
GO:0045910	negative regulation of DNA recombination	37	4	0.15	26.67