Table 1.
Demographic Characteristics, Antimicrobial Susceptibility Profile, Carbapenem MICs of the GIM-1- and SIM-1 Producing Enterobacteriaceae Isolates
| Carbapenemase Producing Enterobacteriaceae blagenes | K. pneumoniae SIM-1 | K. pneumoniae GIM-1 |
E. coli GIM-1 |
E. coli GIM-1 |
E. cloacae GIM-1 |
|---|---|---|---|---|---|
| Location of Patient and Hospital Admission/Day | Respiratory Ward /7 Days | Respiratory Ward/>7 Days | Medicine Ward/<7 Days | Renal Ward/>7 Days | Respiratory Ward/7>Days |
| Specimen/Diagnosis | Sputum/LRTI | Sputum/LRTI | W/S-POWI | Urine/UTI | Sputum/LRTI |
| Antimicrobial susceptibility pattern (mm) | |||||
| Amoxicillin/clavulanic acid | R | R | R | R | R |
| Ampicillin | R | R | I | S | I |
| Cefotaxime | R | R | R | R | R |
| Ceftazidime | R | R | R | R | R |
| Ceftriaxone | R | R | R | R | R |
| Aztreonam | I | R | R | R | R |
| Imipenem | R | R | R | R | R |
| Meropenem | R | R | R | R | R |
| Ertapenem | R | R | R | R | R |
| Gentamicin | R | R | R | R | R |
| Tobramycin | R | R | S | S | S |
| Amikacin | R | S | S | R | S |
| Tetracycline | R | R | S | R | S |
| Ciprofloxacin | R | I | I | I | S |
| Norfloxacin | R | I | R | R | I |
| Nalidixic acid: NA | R | I | I | S | I |
| Co-trimoxazole | R | R | R | S | S |
| Colistin | I | R | S | S | S |
| MIC test (µg/mL) | |||||
| Imipenem | 8 | 32 | 32 | 16 | 16 |
| Meropenem | 16 | 32 | 32 | 32 | 32 |
Note: Inhibition zone by mm according CLSI-2018.
Abbreviations: W/S, wound swab; POWI, postoperative wound infection; LRTI, lower respiratory tract infection; UTI, urinary tract infection; MIC, minimum inhibitory concentration; R, resistant; I, intermediate; S, susceptible.