Table 2.
Laboratory Parameters at the Time of VV-ECMO or VA-ECMO Cannulation and at Their Peak
| VV-ECMO, initiation | p value | VV-ECMO, peak values | p value | VA-ECMO, initiation | |||
|---|---|---|---|---|---|---|---|
| Survivors | Deceased | Survivors | Deceased | ||||
| Creatinine (mg/dl) | 0.66 (0.58–0.92) | 0.84 (0.56–1.24) | 0.70 | 1.07 (0.8–2.8) | 2.24 (1.25–3.24) | 0.93 | 1.36 (1.04–2.10) |
| Hemoglobin (g/dl) | 10.30 (10.00–11.70) | 11.40 (10.40–12.3) | 0.57 | 11.20 (10.80–11.60) | 11.60 (10.80–12.40) | 0.41 | 12.20 (10.20–12.40) |
| D-dimer (µg/ml) | 2.90 (2.10–3.90) | 6.60 (3.30–11.20) | 0.06 | >20 | >20 | 0.70 | 4.90 (1.00–12.20) |
| Albumin (g/dl) | 2.80 (2.10–3.00) | 2.10 (1.80–2.40) | 0.13 | 3.40 (3.15–3.95) | 3.30 (2.70–3.70) | 0.49 | 2.60 (2.20–2.60) |
| AST (U/L) | 47 (39–81) | 64 (44–83) | 0.87 | 128 (102–463) | 134 (115–199) | 0.42 | 187 (83–584) |
| ALT (U/L) | 51 (36–55) | 60 (42–80) | 0.20 | 212 (156–300) | 112 (94–182) | 0.30 | 81 (47–163) |
| Bilirubin (mg/dl) | 0.6 (0.55–0.66) | 0.8 (0.53–1.85) | 0.07 | 2.60 (0.85–5.56) | 2.20 (1.60–14.50) | 0.24 | 0.60 (0.40–0.90) |
| INR | 1.24 (1.08–1.36) | 1.37 (1.20–1.55) | 0.22 | 1.41 (1.36–2.00) | 1.90 (1.46–2.20) | 0.40 | 1.40 (1.10–1.80) |
| CRP (mg/L) | 180 (142–220) | 160 (82–220) | 0.84 | 270 (180–300) | 275 (213–305) | 0.97 | 400 (9.60–170) |
| IL-6 (pg/ml) | - | - | - | 1,878 (1,270–2,810) | 2,679 (548–14,319) | 0.36 | - |
| Troponin-I (µg/L) | - | - | - | 0.98 (0.67–4.50) | 0.05 (0.02–0.08) | 0.32 | - |
Data are shown as median (IQR).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, C-reactive protein; IL-6, interleukin-6; INR, international normalized ratio; IQR, interquartile range; VA-ECMO, venoarterial extracorporeal membrane oxygenation; VV-ECMO, venovenous extracorporeal membrane oxygenation.