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. 2017 Jul 20;145(12):2436–2444. doi: 10.1017/S0950268817001443

Table 1.

Comparisons between tests or associations of tests for the detection of VL in dogs

Compared tests (TEST 1/TEST 2) +/+ (a) +/− (b) −/+ (c) −/− (d) total (n) po BI PI PABAK 95% CI PABAK κ 95% CI κ Δ (%) 95% CI Δ (%)
Sampling 1 (974 cases)
ELISA/DPP 55 158 32 729 974 0805 0129 −0692 0610 0560–0660 0275 0203–0346 12·9 10·6–14·9
LN/BL 32 197 5 740 974 0793 0197 −0727 0585 0534–0636 0187 0127–0248 19·71 18·4–20·4
DPP/BL 25 62 12 875 974 0924 0051 −0873 0848 0815–0881 0·37 0259–0480 5·13 3·55–6·28
LN/ELISA 106 123 107 638 974 0764 0016 −0546 0528 0474–0581 0327 0258–0396 NS
LN/DPP 60 169 27 718 974 0799 0146 −0676 0598 05 470−648 0288 0218–0357 14·6 12·3–16·4
ELISA/BL 28 185 9 752 974 0801 0181 −0743 0602 0551–0652 0·17 0108–0232 18·1 16·5–19·1
[LN or BL]/[ELISA and DPP] 47 187 8 732 974 0800 0184 −0703 0600 0549–0650 0257 0192–0322 18·4 16·8–19·3
[LN or BL]/ELISA 109 125 104 636 974 0765 0022 −0541 0530 0477–0583 0336 0267–0404 NS
[LN or BL]/DPP 60 174 27 713 974 0794 0151 −0670 0587 0536–0638 0·28 0212–0348 15·1 12·8–16·9
Sampling 2 (115 cases)
CS/LN 26 28 16 45 115 0617 0104 −0165 0235 0057–0412 0222 00469–0397 NS
CS/BL 11 43 0 61 115 0626 0374 −0435 0252 0075–0429 0213 00986–0328 37·4 31·2–37·4
CS/DPP 28 26 8 53 115 0704 0157 −0217 0409 0242–0576 0395 0234–0556 15·6 5·2–23·2
CS/ELISA 30 24 12 49 115 0687 0104 −0165 0374 0204–0543 0363 0196–0531 NS
CS/[LN or BL or DPP] 38 16 18 43 115 0704 −0017 −0043 0409 0242–0576 0408 0241–0575 NS
CS/[LN or BL or DPP or ELISA] 42 12 22 39 115 0704 −0087 0026 0409 0242–0576 0413 0249–0576 NS
[LN or BL or CS]/[ELISA and DPP] 25 45 1 44 115 0600 0383 −0165 0200 0021–0379 0285 0167–0403 38·3 30·8–40·0
[LN or BL or CS]/ELISA 37 33 5 40 115 0670 0243 −0026 0339 0167–0511 0376 0230–0521 24·3 14·5–30·1
[LN or BL or CS]/DPP 34 36 2 43 115 0670 0296 −0078 0339 0167–0511 0389 0255–0523 29·6 21·3–32·6

NS, non-significant; (+), positive result; (−), negative result; CI, confidence interval; po, observed agreement (po = (a+d)/n); BI, bias index (BI = (b–c)/n); PI, prevalence index (PI = (a–d)/n); PABAK, prevalence-adjusted bias adjusted κ; Δ, difference in paired proportions, calculated by using McNemar test.