Table 3.
Laboratory biomarkers of COVID-19 patients according to the presence or absence of post-COVID fatigue at 6- and 12-month follow-ups
| Post-COVID fatigue (n = 300) | No post-COVID fatigue (n = 112) | p value | |
|---|---|---|---|
| 6-month follow-up period | |||
| Hemoglobin,* g/dL | 13.8 (1.6) | 14.3 (1.35) | 0.01* |
| Lymphocyte,* ×109/L | 1.12 (0.45) | 1.00 (0.4) | 0.025* |
| Neutrophils,* ×109/L | 5.05 (2.6) | 5.70 (2.9) | 0.043* |
| NLR | 4.5 (4.5) | 5.65 (4.2) | 0.185 |
| Platelets,* ×109/L | 225.8 (73.2) | 453.7 (102.4) | 0.017* |
| Glucose, mg/mL | 118.0 (36.0) | 122.0 (32.0) | 0.347 |
| CK, mg/L | 103.5 (45.0) | 104.0 (31.0) | 0.857 |
| ALT, U/L | 47.5 (38.9) | 52.0 (37.0) | 0.287 |
| AST, U/L | 47.0 (32.7) | 50.1 (30.5) | 0.425 |
| LDH, U/L | 277.5 (95.0) | 288.5 (92.5) | 0.366 |
| CRP, mg/L | 79.0 (89.1) | 90.4 (72.6) | 0.258 |
| D-dimer, ng/mL | 971.8 (940.9) | 951.0 (903.0) | 0.793 |
|
| |||
| Post-COVID fatigue (n = 187) | No post-COVID fatigue (n = 225) | p value | |
|
| |||
| 12-month follow-up period | |||
| Hemoglobin, g/dL | 13.9 (1.5) | 14.0 (1.4) | 0.898 |
| Lymphocyte,* ×109/L | 1.13 (0.45) | 1.03 (0.4) | 0.045* |
| Neutrophils,* ×109/L | 5.15 (2.6) | 5.50 (2.8) | 0.04* |
| NLR | 4.5 (3.0) | 5.45 (5.1) | 0.195 |
| Platelets,* ×109/L | 274.5 (86.5) | 425.5 (95.6) | 0.01* |
| Glucose, mg/mL | 112.0 (38.0) | 121.0 (30.5) | 0.445 |
| CK, mg/L | 102.3 (46.0) | 107.5 (35.0) | 0.317 |
| ALT, U/L | 46.1 (32.2) | 50.2 (36.7) | 0.322 |
| AST, U/L | 47.5 (30.5) | 46.0 (24.5) | 0.691 |
| LDH, U/L | 275.0 (99.0) | 279.1 (89.0) | 0.741 |
| CRP, mg/L | 79.5 (69.0) | 90.3 (101.5) | 0.320 |
| D-dimer, ng/mL | 1,020.0 (846.5) | 1,027.3 (772.1) | 0.855 |
n, number; SD, standard deviation. * Statistically significant differences between groups (p < 0.05).