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. 2022 May 30;39(11):110969. doi: 10.1016/j.celrep.2022.110969

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© 2022 The Author(s)

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Genetic evolution of coronaviruses in Alphacoronavirus and Betacoronavirus

(A and B) Maximum likelihood tree of Alphacoronavirus (A) and Betacoronavirus (B) reconstructed by RAxML based on the polymerase (RdRP) gene, using the PROTCATLG substitution model and 1,000 bootstrap value. Representative isolate sequences used in the present study were downloaded from GenBank and the RdRP gene was intercepted, and the corresponding GenBank accession numbers were provided in the tree. The hosts of the viruses are indicated by different colors (bat, black; human, dark red; pig, magenta; pangolin, blue; and civet, dark green) and by pictograms in the same color. Trees were rooted on midpoint, and branches of the tree labeled in different colors indicate the indicated subgenera.