TABLE 5.

Comparison of patients with RpSTS gliomas to neurotypical control participants.

(A) Auditory semantic matching
Contrast	Patients	NC > Patients		Patients > NC
		+51 −25 +5	+45 −28 +5	−39 −34 +5
Auditory semantic	A, B, and C	5.1	5.4	6.8
matching > Rest	Patient A	2.7	3.2	1.9
	Patient B	3.2	3.5	5.1
	Patient C	3.3	3.0	5.4
Auditory > Visual	A, B, and C	5.9	4.5	5.1
semantic matching	Patient A	3.5	3.3	1.7
	Patient B	4.8	3.0	3.7
	Patient C	2.4	1.9	4.1
(B) Object naming
Contrast	Patients	Patients > NC
		+51 −25 +5	+42 −34 −4	+39 −40 +11
Object naming	A, B, and C	5.2	5.5	7.9
> Rest	Patient A	3.3	5.3	8.5
	Patient B	5.3	2.0	1.8
	Patient C	ns	2.8	2.7
Object naming	A, B, and C	ns	4.9	7.4
> Visual semantic matching	Patient A	1.8	3.9	7.9
	Patient B	3.8	1.9	2.7
	Patient C	ns	2.3	2.3
(C) Task by group interactions
Contrast	Patients	Patients > NC
		+51 −25 +5	+45 −28 +5	−39 −34 +5
Auditory semantic	A, B, and C	ns	ns	3.6
matching > Naming	Patient A	ns	ns	1.7
	Patient B	ns	ns	2.2
	Patient C	ns	ns	2.9
Naming > Auditory	A, B, and C	7.1	5.3	ns
semantic matching	Patient A	4.2	4.1	ns
	Patient B	5.9	3.3	ns
	Patient C	3.1	2.3	ns

Group differences in fMRI activation, for patients with RpSTS gliomas (A, B, C) compared to 61 neurotypical control participants (NC) for: (A) auditory semantic matching, (B) object naming and (C) the interaction of auditory semantic matching and object naming. Co-ordinates (MNI) are from the comparison of all three patients (A, B, and C) to NC. Z-scores for individual patients are all within a 3 mm sphere of these co-ordinates. Statistical thresholds: Z scores ≥ 4.8 = p < 0.05 after family wise error correction across the whole brain (shown in bold), ≥ 3.1 = p < 0.001 uncorrected and ≥ 1.7 = p < 0.05 uncorrected. ns = not significant at p < 0.05 uncorrected. See Figure 3 and text for anatomical localisation.