Table 1.
Association between miR-222-3p expression and clinicopathological features in PTC.
| Clinicopathological features | n | miR-222-3p score, median (interquartile range) | P value | |
|---|---|---|---|---|
| Age | <55 | 54 | 5 (3-8) | p=0.3162 |
| ≥55 | 16 | 7 (4-8) | ||
| Sex | Male | 28 | 7 (4-8) | p=0.5126 |
| Female | 42 | 4 (3-8.25) | ||
| Multicentricity | No | 44 | 7 (3-9) | p=0.3176 |
| Yes | 24 | 5 (3-8) | ||
| Extrathyroidal extension | No | 62 | 6 (3-8) | p=0.9306 |
| Yes | 6 | 5 (4-9) | ||
| Unknown | 2 | / | / | |
| Mutation status | BRAFWT | 19 | 3 (2-4) | p < 0.0001 |
| BRAFV600E | 51 | 8 (4-12) | ||
| TNM stage | I | 57 | 6 (3-8) | p=0.2626 |
| II/III/IV | 13 | 8 (4-10) | ||
| T category | Tx | 2 | / | / |
| T1/T2 | 48 | 5 (2.25-8) | p=0.1017 | |
| T3/T4 | 20 | 6 (4-12) | ||
| N category | N0 | 25 | 3 (2-4) | p < 0.0001 |
| N1 | 45 | 8 (4-12) | ||
| M category | M0 | 69 | 6 (3-8) | / |
| M1 | 1 | 4 |
TNM, tumor node metastasis;. TNM, stage according to the eighth edition of AJCC.