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Somatic variant analysis between high- and low-risk groups in TCGA. (A) Top 15 mutated genes in high- and low-risk groups. (B) Landscape of somatic mutations in TCGA-KIRC cohort. (C) Comparison of top five mutated genes in high- and low-risk groups. Differences in tumor mutation burden (D) and copy number alteration burden (E) between the high- and low-risk groups ** 0.001 < p < 0.01; ****p < 0.0001.
