Table 3.
Outcomes | Bag-mask ventilation (n = 61) | Apneic oxygenation (n = 77) | Adjusted mean difference or odds ratiob (95% confidence intervals) |
---|---|---|---|
Primary outcome | |||
Lowest oxygen saturationa, median [IQR], % | 96 (89, 100) | 92 (84, 99) | 4.23 (0.67 to 7.79) |
Secondary outcome | |||
Lowest oxygen saturation <80%, No. (%) | 4 (6.6) | 12 (15.6) | 0.33 (0.09 to 1.18) |
Exploratory procedural outcome | |||
Lowest oxygen saturation <90%, No. (%) | 17 (27.9) | 34 (44.2) | 0.34 (0.13 to 0.88) |
Lowest oxygen saturation <70%, No. (%) | 2 (3.3) | 6 (7.8) | 0.38 (0.06 to 2.31) |
Successful intubation on first laryngoscopy attempt, No. (%) | 53 (85.9) | 52 (67.5) | 3.50 (1.34 to 9.17) |
Time from induction to successful intubation, median [IQR], seconds | 107 (85, 130) | 132 (88, 205) | −58 (−120.1 to 3.0) |
Operator-reported aspiration, No. (%) | 1 (1.6) | 0 (0.0) | c |
Peri-procedural cardiac arrest, No. (%) | 2 (3.3) | 3 (3.9) | 0.55 (0.05 to 5.84) |
Exploratory clinical outcomes | |||
Ventilator-free days, median [IQR] | 19 (0, 26) | 17 (0, 26) | −1.15 (−5.10 to 2.81) |
ICU-free days, median [IQR] | 17 (0, 24) | 18 (0, 25) | −0.71 (−4.30 to 2.89) |
Died before hospital discharge, No. (%) | 23 (37.7) | 27 (35.1) | 1.20 (0.53 to 2.72) |
Lowest oxygen saturation was missing for 3 patients (2.2%); 2 in the bag-mask ventilation group and one patient in the apneic oxygenation group.
Multivariable regression model includes age (years), body mass index (kg/m2), Acute Physiology and Chronic Health Evaluation II score, and oxygen saturation (%) at induction as covariates.
Unable to calculate given low numbers of patients with values in one or both groups.