Table 2.
Ovarian and Adrenal Hormone Milieu Pre- and Post-Menarche
| Statistic | ||||||
|---|---|---|---|---|---|---|
| Hormone | Mean | Std.Dev | MASD | MSSD | MIN | MAX |
| E2 pg/mL(n=52) | ||||||
| pre-menarchal | 0.37 | 0.35 | 0.22 | 2.03 | 0.15 | 1.10 |
| post-menarchal | 0.63 | 0.48 | 0.54 | 0.84 | 0.15 | 5.00 |
| F statistics | 4.77* | 0.22 | 5.12* | 0.30 | ||
| E1 pg/mL (n=52) | ||||||
| pre-menarchal | 0.84 | 0.26 | 0.27 | 0.14 | 0.20 | 2.50 |
| post-menarchal | 1.48 | 0.80 | 0.92 | 2.07 | 0.20 | 7.50 |
| F statistics | 38.57*** | 28.63*** | 32.53*** | 11.31** | ||
| T pg/mL (n=52) | ||||||
| pre-menarchal | 5.21 | 1.44 | 1.50 | 7.54 | 1.50 | 23.00 |
| post-menarchal | 7.78 | 2.76 | 2.95 | 19.30 | 1.50 | 30.00 |
| F statistics | 8.20** | 10.14** | 12.78** | 3.85 | ||
| A4 pg/mL (n=52) | ||||||
| pre-menarchal | 65.32 | 14.28 | 15.07 | 390.65 | 6.00 | 167.00 |
| post-menarchal | 94.91 | 26.79 | 29.49 | 1708.49 | 17.00 | 287.00 |
| F statistics | 7.37** | 18.80*** | 19.10*** | 15.50*** | ||
| DHEA pg/mL (n=52) | ||||||
| pre-menarchal | 56.66 | 15.16 | 15.97 | 437.30 | 8.50 | 152.00 |
| post-menarchal | 92.98 | 30.01 | 33.06 | 2439.23 | 8.50 | 319.00 |
| F statistics | 15.60*** | 9.95** | 16.01*** | 9.20** | ||
| DHEA-S ng/mL (n=35) | ||||||
| pre-menarchal | 1.63 | 0.54 | 0.65 | 1.07 | 0.20 | 6.80 |
| post-menarchal | 3.67 | 1.43 | 1.63 | 7.03 | 0.30 | 19.40 |
| F statistics | 6.32* | 7.33* | 6.57* | 4.25* | ||
| 7-keto DHEA pg/mL (n=52) | ||||||
| pre-menarchal | 74.95 | 14.76 | 14.95 | 449.50 | 13.00 | 181.00 |
| post-menarchal | 91.58 | 19.23 | 22.33 | 841.84 | 13.00 | 262.00 |
| F statistics | 2.78 | 3.69 | 7.92** | 4.13* | ||
| 17-OHP4 pg/mL (n=52) | ||||||
| pre-menarchal | 12.02 | 4.70 | 5.27 | 66.15 | 1.00 | 52.00 |
| post-menarchal | 22.62 | 9.31 | 10.05 | 268.14 | 1.00 | 133.00 |
| F statistics | 7.74** | 8.69** | 6.66* | 5.43* | ||
| Pregs pg/mL (n=35) | ||||||
| pre-menarchal | 50.46 | 19.35 | 20.80 | 1582.33 | 8.00 | 366.00 |
| post-menarchal | 73.24 | 30.95 | 35.97 | 5309.13 | 14.00 | 592.00 |
| F statistics | 1.98 | 1.04 | 1.32 | 0.94 | ||
| Aldo pg/mL (n=52) | ||||||
| pre-menarchal | 29.28 | 21.84 | 23.93 | 1643.24 | 1.50 | 271.00 |
| post-menarchal | 27.54 | 21.51 | 24.19 | 1298.81 | 1.50 | 158.00 |
| F statistics | 0.19 | 0.01 | 0.00 | 0.18 | ||
Note. Estradiol (E2; limit of detection (LoD)=0.24 pg/mL), Estrone (E1; LoD=0.4 pg/mL), Testosterone (T; LoD=3.2 pg/mL), Androstenedione (A4; 1.1 pg/mL), Dehydroepiandrosterone (DHEA; LoD=17.1 pg/mL), Dehydroepiandrosterone-Sulfate (DHEA-S; LoD=0.04 ng/mL),7-keto Dehydroepiandrosterone (7k-DHEA; LoD=26 pg/mL) 17-hydroxyprogesterone (17-OHP4; LoD=2.3 pg/mL), Pregnenlone-Sulfate (pregs; LoD=1.3 pg/mL), Aldosterone (aldo; LoD=3.3 pg/mL). Standard deviation (sd), mean absolute successive difference (MASD), mean squared successive difference (MSSD).
*
p<0.05
**
p<.01
***
p<.0001.