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. Author manuscript; available in PMC: 2022 Oct 11.
Published in final edited form as: Nat Biomed Eng. 2022 Apr 11;6(5):559–568. doi: 10.1038/s41551-022-00876-4

ED Fig. 1. Clinical Cerenkov imaging system based on the Lightpoint fiberscope design.

ED Fig. 1

A) The Cerenkov camera (Andor iXon Ultra 897 EMCCD, Andor Technology Ltd., Belfast, UK) enclosed in a lead shielded box (background) with a connecting fiberscope to a preclinical enclosure (foreground). B) Clinical enclosure (Lightpoint Medical Ltd., Chesham, UK) containing a reclining chair for patient imaging. The fiberscope (Lightpoint Medical Ltd., Chesham, UK) is installed through the rear of the enclosure opposite the dual track shroud system (red box inset). The fiberscope is held in place via a three-axis articulating arm containing a cerrobend baffle to reduce gamma and beta strikes to the fiber (green box inset). A 17 mm C-mount lens with an f# of 0.95 was used to collect CL (Xenon 0.95/17, Jos. Schneider Optische Werke GmbH, Bad Kreuznach, GM) C) Example of both shrouds deployed to prevent ambient light from reaching the patient during CLI.