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. 2022 May 16;9:896810. doi: 10.3389/fcvm.2022.896810

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Copyright © 2022 Liu, Wang, Guo, Yang, Huang, Li, Wang, Qin and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROC curves of IL-12p70, IL-17, HDL-C and their combination showing different abilities to predict severe CAD. The AUC of the serum IL-12p70 level was 0.652 (95 %CI: 0.604–0.699, P < 0.001), the AUC of the serum IL-17 level was 0.644 (95 %CI: 0.596–0.692, P < 0.001), the AUC of the HDL-C level was 0.665 (95 %CI: 0.617–0.713, P < 0.001), the AUC of the model A(combined IL-12p70, IL-17 and HDL-C) was 0.723 (95 %CI: 0.679–0.767, P < 0.001), and the AUC of the model B (combined IL-12p70, IL-17, HDL-C, gender and diabetes) was 0.752 (95 %CI: 0.710–0.794, P < 0.001).