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. 2022 May 21;14:100190. doi: 10.1016/j.metop.2022.100190

Table 2.

Baseline and changes in outcome measurements after 8 weeks (N = 52).

Variable Group Mean (SD)
Before
Mean (SD)
After
Mean difference
(after-before)
95% Confidence Interval of the Difference P-value
within groups
P-value
between groups
BMI(kg/m2) LS 46.23 ± 4.57 45.01 ± 4.44 −1.21 −1.79)-(-0.63)) 0.00 0.02
LP 46.42 ± 3.67 46.32 ± 3.91 −0.10 −1.95)-(1.73)) 0.90
AST LS 35.81 ± 16.57 30.22 ± 15.94 −5.59 −6.90)-(-4.19)) 0.00 0.00
LP 41.24 ± 12.29 40.04 ± 13.39 −1.20 −2.70)-(0.30)) 0.12
ALT LS 39.64 ± 17.98 34.59 ± 17.44 −5.05 −6.72)-(-3.38)) 0.00 0.01
LP 43.84 ± 11.99 47.68 ± 10.88 3.84 −1.05)-(8.73)) 0.11
AST/ALT ratio LS 0.96 ± 0.20 0.85 ± 0.29 −0.10 −0.19)-(-0.03)) 0.04 0.04
LP 0.93 ± 0.33 0.92 ± 0.41 −0.07 −0.57)-(0.42)) 0.76
NAFLD Score LS −0.72 ± 1.63 −0.67 ± 1.15 0.05 −0.37)-(0.49)) 0.78 0.75
LP −0.34 ± 1.63 −0.34 ± 1.64 −0.009 −0.09)-(0.00)) 0.17
Fib4 Score LS 0.71 ± 0.32 0.69 ± 0.30 0.20- −0.07)-(0.03)) 0.42 0.90
LP 0.66 ± 0.32 0.63 ± 0.33 −0.20 −0.46)-(0.00)) 0.42

LS, lifestyle modification + silymarin; LP, lifestyle modification + placebo.