TABLE 1.
Baseline characteristics of HD patients.
| All N = 76 | Group A (IDWG≥3 kg) N = 25 | Group B (IDWG<3 kg) N = 51 | p-value | |
|---|---|---|---|---|
| Demographic Information | ||||
| Age, years | 62.0 [48.3–69] | 51.0 [44.5–60.5] | 66.0 [50.0–71.0] | 0.003 |
| Gender (male) | 48 (63.2%) | 18 (72.0%) | 30 (58.8%) | 0.263 |
| Dialysis vintage,years | 3.0 [1.25–5.75] | 3.0 [2.0–5.5] | 3.0 [1.0–6.0] | 0.666 |
| Dry weight, kg | 63.9 [57.9–70.1] | 66.5 [62.4–76.1] | 60.9 [53.4–68.6] | 0.019 |
| BMI, kg/m2 | 23.1 ± 3.9 | 24.1 ± 3.6 | 22.6 ± 4.0 | 0.116 |
| IDWG, kg | 2.5 ± 1.0 | 3.6 ± 0.6 | 1.9 ± 0.6 | <0.001 |
| IDWG/Dry Weight, % | 3.9 ± 1.4 | 5.2 ± 0.6 | 3.2 ± 1.1 | <0.001 |
| SBP, mmHg | 143.4 ± 20.1 | 143.8 ± 22.5 | 143.2 ± 19.1 | 0.900 |
| DBP, mmHg | 77.6 ± 12.2 | 77.6 ± 11.8 | 77.5 ± 12.5 | 0.986 |
| Laboratory test | ||||
| Albumin, g/L | 39.3 ± 4.2 | 38.3 ± 3.2 | 39.8 ± 4.5 | 0.142 |
| Scr, μmol/L | 800.8 [683.0–1065.6] | 910.0 [690.3–1185.8] | 771.6 [678.7–1018.3] | 0.116 |
| BUN, mmol/L | 25.4 ± 6.5 | 27.3 ± 6.0 | 24.5 ± 6.5 | 0.072 |
| TC, mmol/L | 4.4 ± 1.2 | 4.1 ± 1.0 | 4.5 ± 1.3 | 0.298 |
| TG, mmol/L | 1.9 [1.4–2.6] | 1.8 [1.2–2.4] | 1.94 [1.41–2.69] | 0.370 |
| Calcium, mmol/L | 2.3 ± 0.2 | 2.3 ± 0.2 | 2.3 ± 0.2 | 0.083 |
| Phosphate, mmol/L | 1.8 ± 0.4 | 1.9 ± 0.4 | 1.8 ± 0.5 | 0.118 |
| Iron, μmol/L | 12.9 ± 6.3 | 11.5 ± 4.8 | 13.5 ± 6.9 | 0.197 |
| Ferritin, μg/L | 144.6 [78.6–434.5] | 98.7 [63.1–175.7] | 214.1 [99.0–536.4] | 0.007 |
| Transferrin, g/L | 1.7 ± 0.3 | 1.8 ± 0.4 | 1.7 ± 0.3 | 0.293 |
| iPTH, pg/ml | 225.1 [87.5–484.7] | 345.8 [88.6–790.3] | 187.3 [85.1–430.5] | 0.146 |
| Comorbidities | ||||
| Diabetes | 28 (36.8%) | 11 (44.0%) | 17 (33.3%) | 0.365 |
| Hypertension | 60 (78.9%) | 22 (88.0%) | 38 (74.5%) | 0.175 |
| Stroke | 11 (14.5%) | 4 (16.0%) | 7 (13.7%) | 1.000 |
| Pulmonary infection | 3 (3.9%) | 1 (4.0%) | 2 (3.9%) | 1.000 |
| Vasculitis | 1 (1.3%) | 0 (0.0%) | 1 (2.0%) | 1.000 |
| SLE | 1 (1.3%) | 1 (4.0%) | 0 (0.0%) | 0.329 |
| CAD | 15 (19.7%) | 5 (20.0%) | 10 (19.6%) | 1.000 |
| Heart failure | 8 (10.5%) | 4 (16.0%) | 4 (7.8%) | 0.490 |
| Drugs | ||||
| β-blocker | 33 (43.4%) | 13 (52.0%) | 20 (39.2%) | 0.291 |
| ACEI/ARB | 17 (22.4%) | 4 (16.0%) | 13 (25.5%) | 0.351 |
BMI, body mass index; IDWG, interdialytic weight gain; SBP, systolic blood pressure at baseline; DBP, diastolic blood pressure at baseline; Scr, serum creatinine; BUN, blood urea nitrogen; TC, total cholesterol; TG, triglyceride; iPTH, intact parathyroid hormone; SLE, systemic lupus erythematosus; CAD, coronary artery disease; ACEI/ARB, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers.