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. 2022 Mar 4;15(2):153–159. doi: 10.21053/ceo.2021.00857

Fig. 2.

Fig. 2.

Expression of monocyte markers in the basal turn of the cochlea. The lateral cochlear wall shows (A) CX3CR1+ resident macrophages before noise exposure and (B) a significant increase in Ly6Cpositive monocytes 1 day after noise exposure. (C) Three days after noise exposure, the cochlea displayed a decrease in Ly6C-positive monocytes and an increase in CX3CR1+ macrophages. The cochlea (D) 5, and (E) 7 days after noise exposure. The dim white color indicates non-specific staining of Ly6C to fibrocytes, and the weak white color with a hollow center indicates blood vessel endothelium, which is also known to express Ly6C. In all of the images, the top is the lateral wall and the bottom is the basilar membrane. Dotted line indicates Ly6C-stained endothelial cells of the blood vessel that are confirmed by exploration of z-stack images. Green, CX3CR1; White, Ly6C. Scale bar=100 μm.