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. 2022 May 16;10:864787. doi: 10.3389/fbioe.2022.864787

TABLE 2.

Reported high-yield GA production in recent years.

Strains Fermentation Type GA (g/L) Volumetric Productivity (g/L/h) References
A. niger batch culture in air-lift bioreactor 150 2.3 Klein et al. (2002)
A. niger AN151 submerged fermentation 330 21.0 ± 0.9 Lu et al. (2015)
A. niger JCM 5549 immobilization/batch 272 6.1 Matsui et al. (2013)
A. niger SIIM M276 batch 76.67 0.86 Zhang et al. (2016)
A. niger NCIM 548 immobilization/batch 92 2.04 Mukhopadhyay et al. (2004)
A. niger IAM 2094 batch 80–100 1.13 Ikeda et al. (2006)
A. niger ORS-4410 batch 80.60 0.131 Singh et al. (2003)
A. niger ORS-4410 semi-continuous batch 110.94 0.9375 Singh, (2008)
A. pullulans (De Bary) DSM 7085 continuous batch in a cascading operation of two bioreactors 350–370 12.7–13.9 Anastassiadis and Rehm, (2006b)
P. variabile P16 double feeding fed-batch 240 2.02 Crognale et al. (2008)
G. oxydans NBIMCC 1043 batch 148.5 9.03 Velizarov and Beschkov, (1994)
G. oxydans DSM2003 cascade hydrolysis/batch fermentation 118.9 1.65 Hou et al. (2018)
Klebsiella pneumoniae Δgad fed-batch 422 4.22 Wang et al. (2016)