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. 2022 May 16;13:796933. doi: 10.3389/fneur.2022.796933

Figure 2.

Figure 2

Intracellular function of vitamin D. VitD typically acts as a transcription factor in association with retinoid-X-receptors (RXR) to mediate gene transcription at VitD response elements in promoter regions of genes. However, VitD can have immediate effects on cell function (non-genomic) via interaction with PDIA3 that leads to changes in calcium transport.