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. 2022 May 16;13:844341. doi: 10.3389/fneur.2022.844341

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Copyright © 2022 Kim, Choi, Chin, Lee and Na.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The fixation duration. (A) The total fixations duration was longer in both patient groups with AD than among the NC participants. (B) Patients with EOAD and LOAD showed longer fixation durations on the perceptual space AOI than NC participants. (C) Patients with EOAD showed longer fixation durations on the working space AOI than LOAD and NC participants. (D) Patients with EOAD and LOAD showed a lower ratio (working/perceptual space) of fixation durations on the AOIs than NC participants. AOI, area of interest; EOAD, early-onset Alzheimer's disease; LOAD, late-onset Alzheimer's disease; NC, normal control. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.