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. 2022 May 30;22:319. doi: 10.1186/s12887-022-03359-2

Table 3.

Multiple regression analysis of the association of demographic and clinical characteristics with developmental delays (ASQ-3 scores less than 2 standard deviations below the population mean)

Variable Adjusted odds ratio 95% CI P value
Trimester at SARS-CoV-2 infection 3rd Reference
2nd 8.1 2.4–27.7 0.001*
1st 8.2 1.1–55.9 0.039*
Maternal age 1.04 0.96–1.1 0.305
Gestational age at birth  ≤ 31 weeks 7.7 1.4.-45.8 0.032*
 > 31 Reference
Maternal education (diploma and above) 1.8 0.59–5.4 0.300
Paternal education (diploma and above) 0.5 0.2–1.3 0.172
Male 1.6 0.68–3.5 0.297
Type of feeding in the first 6 months Mixed feeding Reference
Bottle feeding (formula) 1.3 0.46–3.4 0.652
Breastfeeding (breast milk) 0.5 0.14–1.6 0.239

Values are expressed as adjusted odds ratios and 95% confidence intervals (95% CIs)