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. 2022 Apr 19;5(1):85–94. doi: 10.1159/000524086

Table 3.

Molecular docking generated binding parameters between cannabinoids and AChE/BChE

AChE
BChE
Cannabinoid free binding energy, kcal/mol inhibition constant; Ki, μΜ free binding energy, kcal/mol inhibition constant, Ki, μΜ
Δ8-THC –5.5 100 –5.0 236.2
CBG –5.2 144.8 –4.6 431.2
CBGA –4.9 256.8 –3.7 1,860
CBT –5.4 106.1 –5.4 112.2
CBDV –5.9 51.2 –4.4 622.6
Galantamine –8.2 1.03 –5.1 190.6

Galantamine is used as a positive control.