Fig. 1.
H2O2-mediated cytotoxicity and IL-1β release by human bronchial epithelial cells. Unprimed, LPS-, or TNF-primed human bronchial epithelial cells were infected with D39∆cps at MOI 50 in the presence or absence of catalase for 4 and 6 h. Cytotoxicity (a) and IL-1β release (b) were evaluated at the indicated time points. Bars (a) denote mean values ± standard deviation (SD). The data in (b) are displayed as box plots. The level of significance was determined using Kruskal-Wallis test with Dunn's post-test (n ≥ 4; *p < 0.05; **p < 0.01; ***p < 0.001).