Table 1.
- Comparison of plasma and placental OS markers in IUGR and HP groups.
| OS markers | HP group (n=25) | IUGR group (n=25) | P-value of IUGR compared to HP |
|---|---|---|---|
| Age (years) | 31.20 ± 5.84 | 26.20 ± 3.81 | >0.05 |
| Gestational age (weeks) | 39.00 ± 2.30 | 35.80 ± 2.98 | >0.05 |
| Plasma H2O2 nmol/ml | 8.61 ± 1.11 | 9.78 ± 1.31* | 0.0013 |
| Placental H2O2 µmol/min/mg protein | 2.58 ± 0.31 | 3.67 ± 0.45† | 0.0000 |
| Plasma SOA nmol/ml | 35.20 ± 4.52 | 40.5 ± 5.51* | 0.0005 |
| Placental SOA µmol/min/mg protein | 4.93 ± 0.58 | 6.78 ± 1.31† | 0.0001 |
| Plasma MDA nmol/ml | 5.71 ± 0.68 | 6.46 ± 0.82* | 0.0001 |
| Placental MDA nmol/g | 293.60 ± 36.7 | 415.30 ± 50.5† | 0.0000 |
| Plasma PCC pmol/l | 298.60 ± 38.3 | 339.80 ± 40.5* | 0.0006 |
| Placental PCC nmol/mg | 15.70 ± 1.80 | 23.60 ± 3.34† | 0.0001 |
Values are presented as mean ± SD. *p<0.001; †p<0.0001, OS: oxidative stress, IUGR: intrauterine growth restriction, HP: healthy pregnant, SOA: superoxide anions, H2O2: hydrogen peroxide