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MicroRNAs revealed with upstream network analysis: LR12 + TAK242-treated vs. scrambled peptide and vehicle (30% ethanol)-treated arteries. DEGs with higher expression in scrambled peptide-treated group (log2 > 2, p < 0.05) and with higher expression in LR12 + TAK242-treated group (log2 < −2, p < 0.05).
| Associated with Inhibited Network | DEGs (log2 > 2, p < 0.05) | DEGs (log2 < −2, p < 0.05) |
|---|---|---|
| mir-133 | VCAN | PPARG, TNFSF10 |
| miR-155-5p | BACH1, CD69, CXCL8, PMAIP1, PPL, RIPK1 |
