Table 1.

Fold change in expression levels of antigen-specific mAbs when pairing heavy chains with λ versus κ light chains.

	IgG1			dIgA1			dIgA2			IgM
	Yields (μg/mL)		Fold Difference	Yields (μg/mL)		Fold Difference	Yields (μg/mL)		Fold Difference	Yields (μg/mL)		Fold Difference
	κ	λ	λ/κ	κ	λ	λ/κ	κ	λ	λ/κ	κ	λ	λ/κ
VRC01	252.11 ± 7.09	122.42 ± 3.94	−2	182 ± 17	198.75 ± 17.46	1	2.14 ± 0.3	68.37 ± 8.77	32	60.81 ± 8.29	739.56 ± 62.72	12
Fm-6	8.79 ± 5.38	33.78 ± 13.6	4	17.18 ± 4.73	0.53 ± 0.37	−33	0.09 ± 0.02	1.99 ± 2.28	11	0.004 ± 0.001	77.56 ± 8.67	19,368
33C6	25.1 ± 1.73	1.78 ± 0.4	−14	21.86 ± 11.63	443.96 ± 80.59	20	0.22 ± 0.01	280.7 ± 33.8	1298	0.02 ± 0.01	285.83 ± 35.12	11,630
PGT121	60.45 ± 19.92	56.95 ± 21.38	−1	35.26 ± 5.86	292.72 ± 29.01	8	0.05 ± 0.01	179.37 ± 39.93	3920	0.11 ± 0.01	767.49 ± 89.43	7032