Table 3.
Author (y) | Groups Studied and Interventions | Results and Findings | Conclusions |
---|---|---|---|
Johnson et al. (2012) [53] |
18 healthy volunteers were randomly selected to receive either escalating or de-escalating doses of psilocybin (0, 5, 10, 20, 30 mg) over 5 total, 8 h long sessions. | Mean onset of headache was 7.0 h after administration. The number of participants who reported a headache increased as the dose increased, with nearly all reporting headaches at 30mg. |
Psilocybin causes headaches in a dose-related fashion. |
Ramachandran et al. (2018) [54] |
Case report of a patient who had intractable phantom limb pain after amputation described as a nail boring into the leg. | Psilocybin was paired with MVF, where a nail was visualized by the patient being removed from the leg. | Psilocybin-MVF worked synergistically to eliminate the pain that felt and decreased any paroxysmal episodes. |