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. 2022 May 14;28(18):1981–1995. doi: 10.3748/wjg.v28.i18.1981

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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The co-occurrence network shows the correlations of the colon mucosa microbiota with the differentially expressed genes. Edges: Correlations with P values < 0.01; red edges: Positive correlations; gray edges: Relationship between the genes and the pathways; green nodes: Genes involved in the top seven significantly differential KEGG pathways in the azoxymethane/dextran sulfate sodium salt (AOM/DSS)-FUSO group compared with the AOM/DSS group; orange nodes: The differential bacterial taxa identified by LEfSe analysis; blue nodes: Related pathways of defferentially expressed genes.