Table 4.
Health status, depression, and anxiety in the previous 12 months.
| Outcome, instrument | 12-month chronic cough cohort (n = 389) | Matched non-chronic cough cohort (n = 1164) | p value |
|---|---|---|---|
| Health status, SF-12-v2 | |||
| Physical Component Summary score, mean (SD) | 47.68 (8.25) | 51.44 (8.03) | <0.001 |
| Mental Component Summary score, mean (SD) | 42.42 (9.14) | 45.69 (9.31) | <0.001 |
| Domain scores, mean (SD) | |||
| Physical functioning score | 47.69 (9.79) | 51.87 (8.40) | <0.001 |
| Physical role limitation score | 43.79 (8.76) | 47.94 (8.82) | <0.001 |
| Bodily pain score | 45.07 (9.77) | 49.20 (9.45) | <0.001 |
| General health score | 46.35 (9.91) | 49.25 (9.02) | <0.001 |
| Vitality score | 49.80 (9.08) | 52.51 (8.99) | <0.001 |
| Social functioning score | 42.38 (9.10) | 46.40 (9.23) | <0.001 |
| Emotional role limitations score | 39.23 (10.75) | 43.58 (10.82) | <0.001 |
| Mental health score | 44.57 (9.09) | 47.82 (8.71) | <0.001 |
| Health utility, SF-6D | |||
| Utility score, mean (SD) | 0.65 (0.11) | 0.70 (0.12) | <0.001 |
| Depression, PHQ-9 a | |||
| Total score, mean (SD) | 8.84 (6.64) | 5.78 (5.88) | <0.001 |
| Classification of depression, n (%) a | |||
| None–minimal (score 0–4) | 118 (30.3) | 624 (53.6) | <0.001 |
| Mild (score 5–9) | 116 (29.8) | 289 (24.8) | |
| Moderate (score 10–14) | 84 (21.6) | 136 (11.7) | |
| Moderately severe (score 15–19) | 40 (10.3) | 74 (6.4) | |
| Severe (score 20–27) | 31 (8.0) | 41 (3.5) | |
| Anxiety, GAD-7 | |||
| Mean score (SD) | 6.91 (5.30) | 4.56 (4.53) | <0.001 |
| Classification of anxiety, n (%) a | |||
| None (score 0–4) | 145 (37.3) | 660 (56.7) | <0.001 |
| Mild (score 5–9) | 140 (36.0) | 344 (29.6) | |
| Moderate (score 10–14) | 66 (17.0) | 110 (9.5) | |
| Severe (score 15–21) | 38 (9.8) | 50 (4.3) | |
GAD-7: Generalized Anxiety Disorder-7 scale; NHWS: National Health and Wellness Survey; PHQ-9: Patient Health Questionnaire-9; SD: standard deviation; SF-12v2: Medical Outcomes 12-item Short Form Survey Instrument; SF-6D Short-Form Six-Dimension health index.
aValues indicate the number and percentage (in brackets) of cohort members with that classification; percentages are based on the total number of NHWS respondents in the cohort.