Table 4.
Threshold values, sensitivity, specificity, PPV and NPV for distinguishing grade 2 + 3 IDH-mutant astrocytoma from grade 4 IDH-mutant astrocytoma
| Cut-off | Sensitivity(%) | Specificity(%) | PPV(%) | NPV(%) | |
|---|---|---|---|---|---|
| ADCmin | 0.94 | 100.00 | 85.01 | 66.70 | 96.00 |
| ITSS | 1 | 81.80 | 80.00 | 51.40 | 94.40 |
| rCBVmax | 3.84 | 94.44 | 94.64 | 85.00 | 98.10 |
| ADCmin + ITSS | 94.44 | 91.07 | 77.30 | 98.10 | |
| ADCmin + rCBVmax | 100.00 | 89.29 | 75.00 | 100.00 | |
| ITSS + rCBVmax | 100.00 | 85.71 | 69.20 | 100.00 | |
| ADCmin + ITSS + rCBVmax | 100.00 | 92.86 | 81.80 | 100.00 |
PPV Positive predictive value, NPV Negative predictive value