Table 3.

Histology assessment of kidneys injury in control and PKM2 KO mice. We examined the tubules of the cortical and corticomedullary areas using PAS-stained renal sections obtained from PBS or LPS-treated wild type (Ctrl) and podocyte PKM2 knockout (KO) mice and scored the degree of injury as detailed in the methods section

	Cortical area	Corticomedullary junction
Ctrl-PBS	1.36 ± 0.78	0.85 ± 0.41
KO-PBS	0.51 ± 0.23	0.22 ± 0.10
Ctrl-LPS	16.29 ± 6.59*	14.54 ± 5.78*
KO-LPS	2.77 ± 1.16*#	2.61 ± 1.19#

*p < 0.05 indicates a significant difference between PBS- and LPS-injected mice. ^#p < 0.05 indicates a significant difference between Ctrl and KO mice