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. 2022 May 16;9:821272. doi: 10.3389/fnut.2022.821272

Table 7.

Effect of heat stress and RSV on the levels of cytokines in spleen of 42-day-old broilers (d 14 of heat treatment).

Dietary treatments SEM P -values
NT NT + RSV HT HT + RSV P-RSV P-stress P-RSV × stress
Tuftsin, ng/g 75.81b 86.32b 122.38a 97.47b 5.127 0.354 0.001 0.031
Properdin, ng/g 36.28c 45.33c 87.53a 70.79b 5.038 0.459 <0.001 0.021
FN, μg/g 455.96b 424.82b 711.81a 561.30b 33.610 0.087 0.001 0.250
IL-1β, pg/g 1,533.07c 1,964.51c 4,875.27a 3,011.86b 310.940 0.024 <0.001 0.001
IL-2, pg/g 1,196.72c 1,465.20bc 2,284.60a 1,792.11b 110.252 0.443 <0.001 0.016
IL-4, pg/g 550.15c 648.47c 1,189.15a 891.75b 62.983 0.177 <0.001 0.012
TNF-α, pg/g 238.34c 238.95c 527.82a 373.31b 30.494 0.039 <0.001 0.038
IFN-γ, pg/g 491.59a 587.17a 313.52b 456.98a 28.859 0.011 0.002 0.576

Data are presented as mean ± SEM, n = 6. Values in the same row with different superscript are significantly different (P < 0.05) by one-way ANOVA. P-values (P-RSV, P-Stress, or P-RSV × Stress) ≤ 0.05 indicates RSV, heat stress, or the interaction between heat stress and RSV. RSV, resveratrol; NT, normal temperature; HT, heat stress; FN, fibronectin; IL-1β, Interleukin-1β; IL-2, Interleukin-2; IL-4, Interleukin-4; TNF-α, tumor necrosis factor-α; IFN-γ, interferon γ.