Table 1.
Basic clinical and laboratory characteristics in individual groups
| IBD group (n=58) | CD group (n=31) | UC group (n=27) | healthy controls (n=20) | |
|---|---|---|---|---|
| Age (years) | 15 (13–15) | 15 (13–16) | 15 (13–15) | 15 (12–16) |
| BMI (kg/m 2 ) | 20.3 (17.2–22.5) | 20.3 (17.3–24.0) | 20.0 (17.0–22.1) | 19.1 (16.1–21.5) |
| CRP (mg/l) | 1.1 (0.5–4.2)*** | 1.1 (0.5–8.4)*** | 0.8 (0.5–2.0)** | 0.5 (0.5–0.7) |
| IL-6 (ng/l) | 2.3 (1.4–4.6)*** | 2.4 (1.4–4.1)*** | 1.9 (1.4–4.7)** | 1.4 (1.4–1.6) |
| F-CPT (μg/g) | 419 (145–1071)*** | 532 (111–1636)*** | 403 (183–723)*** | 46 (35–74) |
| Ferritin (μg/l) | 14.0 (7.5–33.6)* | 14.0 (7.1–32.4)* | 16.5 (7.8–36.8)* | 29.0 (15.4–39.0) |
| Hemoglobin (g/l) | 137 (125–147) | 139 (128–148) | 135 (121–146) | 131 (129–136) |
| Thrombocytes (×10 9 /l) | 318 (272–371) | 317 (283–366) | 319 (235–373) | 293 (247–326) |
| Leucocytes (×10 9 /l) | 7.2 (5.4–9.4) | 7.5 (6.1–9.0) | 6.6 (4.8–10.4) | 6.5 (5.6–7.8) |
| TC (mmol/l) | 3.5 (3.0–3.9)** | 3.5 (3.1–3.9)** | 3.6 (3.0–4.2)* | 4.1 (3.7–4.7) |
| LDL-C (mmol/l) | 1.7 (1.4–2.1)** | 1.8 (1.5–2.1)* | 1.7 (1.3–2.2)* | 2.2 (1.9–2.6) |
| HDL-C (mmol/l) | 1.3 (1.0–1.5)* | 1.2 (1.0–1.4)* | 1.4 (1.1–1.5) | 1.5 (1.2–1.7) |
| TG (mmol/l) | 0.9 (0.7–1.4) | 1.0 (0.7–1.4) | 0.9 (0.6–1.4) | 1.1 (0.7–1.6) |
| FG (mmol/l) | 4.9 (4.6–5.1) | 4.8 (4.5–5.1) | 5.0 (4.8–5.2) | 4.8 (4.7–5.0) |
IBD = inflammatory bowel disease; CD = Crohn’s disease; UC = ulcerative colitis; BMI = body mass index; CRP = C-reactive protein; IL-6 = interleukin-6; F-CPT = fecal calprotectin; TC = total cholesterol; LDL-C = LDL-cholesterol; HDL-C = HDL-cholesterol; TG = triglycerides; FG = fasting glycemia. Values are expressed as median and interquartile range (25–75 percentile). Significant differences of patients group versus controls:
*
p<0.05;
**
p<0.01;
***
p<0.001 according to Mann-Whitney U test.