Fig. 1.

Intestinotrophic effects of glepaglutide in male (■) and female (□) Wistar rats. (A) Effects of short-term treatment with glepaglutide on small intestinal weight in male rats (g), (B) Effects of long-term treatment with glepaglutide on small intestinal weight (g) in male and female rats, and (C) Effects of long-term treatment with glepaglutide on small intestinal length (cm) in male and female rats. Data are presented as mean + SD. Statistical analysis were one-way ANOVA followed by Dunnett’s Multiple Comparison tests (A), and one-way ANOVA followed by Shirley’s test for male and female weight and female length during dosing, one-way ANCOVA followed by Williams’ test for male length during dosing. One-way ANCOVA followed by t-test for all during recovery (B and C).