Table 1.
Pooled prevalence of different HIV-1 subtypes stratified by time period, study region and risk group
| CRF01_AE | CRF07_BC | CRF08_BC | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Category | N | Proportion % (95% CI) | P*, I2 | P† | Proportion % (95% CI) | P*, I2 | P† | Proportion % (95% CI) | P*, I2 | P† |
| Region‡ | 0·001 | <0·01 | <0·01 | |||||||
| Northeastern | 22 | 57·80 (45·74–69·44) | <0·01, 94·0% | 4·63 (2·57–7·13) | <0·01, 58·2% | 0·00 (0·00–0·00) | 0·757, 0·0% | |||
| Eastern | 115 | 48·95 (44·17–53·74) | <0·01, 95·7% | 12·47 (9·84–15·35) | <0·01, 93·8% | 1·33 (0·64–2·19) | <0·01, 85·3% | |||
| Central | 27 | 34·41 (24·75–44·72) | <0·01, 94·2% | 19·52 (11·78–28·51) | <0·01, 94·1% | 0·14 (0·00–0·84) | 0·004, 46·8% | |||
| Northwestern | 7 | 22·68 (4·31–48·76) | <0·01, 96·7% | 65·89 (35·98–90·41) | <0·01, 97·3% | 0·00 (0·00–0·39) | 0·153, 36·1% | |||
| Southwestern | 45 | 36·16 (28·16–44·55) | <0·01, 96·1% | 25·94 (18·20–34·46) | <0·01, 96·7% | 13·93 (7·93–21·13) | <0·01, 96·7% | |||
| Time period§ | 0·001 | <0·01 | 0·164 | |||||||
| Before 2000 | 9 | 29·11 (15·37–44·92) | <0·01, 95·5% | 0·59 (0·00–3·92) | <0·01, 85·3% | 0·44 (0·00–3·34) | <0·01, 82·8% | |||
| 2001–2004 | 14 | 28·73 (17·30–41·61) | <0·01, 89·8% | 6·44 (1·74–13·18) | <0·01, 84·2% | 6·72 (1·39–14·72) | <0·01, 88·1% | |||
| 2005–2007 | 34 | 33·30 (22·76–44·69) | <0·01, 97·5% | 10·53 (6·04–15·93) | <0·01, 94·0% | 4·67 (1·60–8·86) | <0·01, 94·1% | |||
| 2008–2010 | 86 | 49·92 (43·96–55·88) | <0·01, 95·6% | 15·04 (11·50–18·92) | <0·01, 93·8% | 2·06 (0·62–4·06) | <0·01, 93·8% | |||
| 2011–2014 | 76 | 48·25 (42·68–53·83) | <0·01, 94·9% | 26·02 (20·90–31·47) | <0·01, 95·6% | 1·96 (0·75–3·57) | <0·01, 91·4% | |||
| Risk group|| | <0·01 | 0·083 | <0·01 | |||||||
| MSM | 121 | 51·28 (46·15–56·40) | <0·01, 96·1% | 19·98 (16·17–24·07) | <0·01, 95·7% | 0·00 (0·00–0·00) | 0·577, 0·00% | |||
| HST | 76 | 38·78 (33·08–44·63) | <0·01, 95·4% | 14·88 (10·96–19·23) | <0·01, 95·0% | 9·81 (6·44–13·70) | <0·01, 95·3% | |||
| Total | 219 | 44·54 (40·81–48·30) | <0·01, 96·0% | 16·45 (13·82–19·25) | <0·01, 95·5% | 2·55(1·56–3·73) | <0·01, 93·3% | |||
N, Number of estimates; CI, confidence interval; MSM, men who have sex with men; HST, heterosexual transmission.
*
P value was calculated by examining Cochran's Q statistic (P < 0·1 was considered statistically significant).
†
P value stand for the differences between groups (P < 0·05 was considered statistically significant).
‡
For time period subgroup analysis, 219 datasets from 129 articles were used.
§
For study region subgroup analysis, 216 datasets from 126 articles were used.
||
For risk group subgroup analysis, 197 datasets from 120 articles were used.
#
Others included unique recombinant forms (URFs) and other subtypes.